Question 1

What is the history and background of Hanabusa IVF?

Accepted Answer

Hanabusa IVF was founded more than a decade ago as a boutique fertility center dedicated to personalized, low‑stimulation IVF. The clinic’s origins trace back to a collaboration between Masahide Shiotani, M.D., Ph.D., founder of the renowned Hanabusa Women’s Clinic in Kobe, Japan, and Dr. Lyndon Chang, a leading pioneer of Minimal Stimulation IVF in the United States. Over the years, Hanabusa IVF has become the premier specialist in Mini IVF and Natural Cycle IVF on the West Coast. Notable milestones include the first successful autologous IVF after ovarian transplantation and the achievement of live births in women up to 49 years old using their own eggs. In the past five years, Dr. Chang has facilitated more than 25 live births for patients aged 45‑49 and over 125 live births for patients with high FSH levels, underscoring the clinic’s expertise in challenging cases such as diminished ovarian reserve and premature ovarian failure.

Question 2

What fertility treatments and services does Hanabusa IVF offer?

Accepted Answer

Hanabusa IVF provides a full spectrum of assisted reproduction services tailored to each patient’s needs. Core IVF offerings include conventional In‑Vitro Fertilization (IVF), Minimal Stimulation (Mini) IVF, and Natural Cycle IVF, all designed to maximize egg quality and pregnancy rates. The clinic also offers Low Complexity IVF, which uses oral medications and local anesthesia for a simplified approach. Additional treatments include intrauterine insemination (IUI), egg freezing for fertility preservation, and comprehensive preimplantation genetic testing (PGT‑A) with embryo culture to the blastocyst stage. For patients requiring donor gametes, Hanabusa IVF runs an in‑house Asian Egg Bank with over 100 screened donors, providing both fresh and frozen donor eggs. Surrogacy coordination, reciprocal IVF for lesbian couples, and dual insemination for gay male couples are also available. Complementary services such as ovarian rejuvenation with platelet‑rich plasma, holistic IVF support, and personalized counseling round out the clinic’s extensive fertility treatment portfolio.

Question 3

Does Hanabusa IVF offer egg donation for IVF treatment?

Accepted Answer

Yes, Hanabusa IVF provides a comprehensive egg donation program as part of its fertility treatment options. The clinic operates an in‑house Asian Egg Bank that features a database of more than 100 screened donors, allowing patients to select fresh or frozen donor eggs that match their genetic preferences. All donors undergo rigorous health, genetic, and infectious‑disease screening to ensure safety and high-quality donor eggs. Recipients receive individualized counseling, donor matching, and coordinated embryo creation, with the option to use preimplantation genetic testing to select the healthiest embryos for transfer. The clinic’s advanced vitrification technique ensures that frozen donor eggs retain high survival rates, contributing to strong pregnancy outcomes for recipients.

Question 4

Does Hanabusa IVF provide fertility treatment for same-sex couples?

Accepted Answer

Hanabusa IVF is fully inclusive of LGBTQ+ families and offers dedicated fertility services for same‑sex couples. Lesbian partners can pursue reciprocal IVF (co‑maternity), where one partner provides the eggs and the other carries the pregnancy, with options ranging from low‑complexity oral‑medication cycles to full‑feature IVF that includes ICSI, embryo freezing, and PGT‑A. Gay male couples have access to an on‑site egg donor and surrogacy program, allowing both partners to contribute sperm to create embryos that are then transferred to a surrogate. The clinic also supports dual insemination, enabling both partners’ sperm to be used in a single cycle. All protocols are designed to maximize embryo quality, pregnancy rates, and a supportive experience for same‑sex families.

Question 5

What IVF laboratory technology does Hanabusa IVF use?

Accepted Answer

Hanabusa IVF operates a state‑of‑the‑art embryology laboratory that adheres to the highest quality standards in assisted reproduction. The lab is a participant in the Progressive Laboratory Program and holds a California Tissue Bank license, FDA registration, and accreditation from the College of American Pathologists (CAP) as well as AAAASF accreditation for its procedure rooms. Embryologists employ vitrification, a flash‑freezing technique developed in Japan, to preserve embryos and oocytes with optimal survival rates. All embryos are cultured to the blastocyst stage using advanced incubators that maintain precise temperature, pH, and gas conditions, enhancing implantation potential during embryo transfer. The laboratory’s senior staff, led by Director Lisa Nelson, M.Sc., includes multiple senior embryologists and bioanalysts who ensure rigorous quality control for each step of the IVF process.

Question 6

Who are the fertility doctors and specialists at Hanabusa IVF?

Accepted Answer

Hanabusa IVF is led by a team of board‑certified fertility specialists. Dr. Diana LeBlanc, MD, FACOG, is a reproductive endocrinologist with extensive experience in in‑vitro fertilization and personalized fertility treatment. Dr. Lyndon Chang, MD, FACOG, serves as Medical Director and is a pioneer of Minimal Stimulation IVF in the United States, focusing on low‑dose protocols for patients with high FSH or diminished ovarian reserve. Dr. Azadeh A. Nezhat, M.D., FACOG, is a board‑certified obstetrician‑gynecologist and minimally invasive surgeon who also contributes to the clinic’s assisted reproduction programs. The clinical team is supported by Disha Mistri, MSN, NP, a certified nurse practitioner who coordinates care for LGBTQ+ families and single patients. In the laboratory, Lisa Nelson, M.Sc., serves as Embryology Laboratory Director, overseeing embryo culture to the blastocyst stage, while senior embryologists such as Monica Velasco and Jade Yoho ensure high‑quality embryo handling. Together, this multidisciplinary group provides comprehensive IVF, embryo transfer, and fertility support.

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