January 23, 2026
RSC Physician Wins Research Award for IVF Breakthrough
Dr. Evan Rosenbluth of Reproductive Science Center received an ASRM In-Training Award for developing non-invasive microRNA testing to detect chromosomal abnormalities in embryos, potentially improving IVF success rates by identifying aneuploidy, the leading cause of IVF failure.
Key Takeaways
Non-Invasive MicroRNA Testing for Embryo Chromosomal Abnormalities
Dr. Rosenbluth’s research identifies microRNA-191 as a biomarker for aneuploidy in embryos, detected through culture media analysis. This non-invasive technique could reduce IVF failure rates by selecting embryos with chromosomal normality.
Aneuploidy as a Leading Cause of IVF Failure
Aneuploidy, characterized by abnormal chromosome counts (e.g., Down syndrome), is the primary reason for IVF cycle failure. Dr. Rosenbluth’s work focuses on early detection to improve pregnancy outcomes.
ASRM In-Training Research Awards Recognize Top IVF Innovations
Only five ASRM in-training awards are given annually for groundbreaking fertility research. Dr. Rosenbluth’s award highlights his contribution to advancing non-invasive diagnostics in reproductive medicine.
MicroRNA Correlation with IVF Success Rates
The study found multiple microRNAs in embryo cultures correlated with live birth potential. Higher levels of microRNA-191 in failed cycles indicate its predictive value for implantation success.
RSC Physician’s Expertise in Endometriosis Research
Dr. Rosenbluth, who joined Reproductive Science Center after a University of Iowa fellowship, has also conducted award-winning research on endometriosis, a condition affecting 6.3 million women in the U.S.
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