January 21, 2026
ERA Test: Personalize Embryo Transfer for Better IVF Success
The Endometrial Receptivity Array (ERA) test analyzes 238 genes to determine the optimal implantation window for embryo transfer, reducing implantation failure risks in IVF. Results help tailor treatment timing, especially for women with prior implantation failures.
Key Takeaways
Who Benefits from the ERA Test: A Guide for IVF Candidates
The ERA test is recommended for women with ≥3 failed IVF embryo transfers (under 37) or ≥2 failures (over 37) and those with genetically tested embryos. It identifies endometrial receptivity issues contributing to infertility.
Understanding the ERA Test Procedure: 3 Simple Steps Explained
The test involves an endometrial biopsy, sample preservation, and genetic analysis. The biopsy is typically performed without anesthesia but mild sedation is available for anxious patients. Results determine if the implantation window is timely or displaced.
Optimal Timing for the ERA Test: Natural vs Hormonal Cycles
In hormonal cycles, the biopsy occurs on day P+5 (120 hours after progesterone). In natural cycles, it’s done on LH+7 (7 days after the LH surge). Artificial LH triggers are often used to standardize timing for testing.
What the ERA Test Analyzes: 238 Key Genes for Endometrial Receptivity
The test evaluates 238 genes linked to endometrial receptivity. Results classify the endometrium as ‘receptive’ (implantation window aligns) or ‘non-receptive’ (window is displaced), guiding personalized embryo transfer scheduling.
Interpreting ERA Test Results and Adjusting Embryo Transfer Timing
If non-receptive, the embryo transfer is delayed to the next cycle following lab recommendations (e.g., adjusting timing by hours/days). Receptive results allow transfers under the same cycle conditions as the biopsy.
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