5 Common Causes of Recurrent Pregnancy Loss & Treatments

Recurrent pregnancy loss (RPL) is defined as two or more consecutive miscarriages before 20 weeks, with genetic abnormalities being the leading cause, especially in women over 35. Untreated thyroid disorders, uterine malformations, cervical insufficiency, and lifestyle factors like smoking also significantly contribute to RPL. Advanced diagnostic tests and treatments such as IVF with genetic screening offer hope for successful pregnancies.

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Key Takeaways

Genetic Chromosomal Abnormalities and IVF Solutions

Chromosomal defects in embryos, particularly in women over 35, are a primary cause of RPL. Karyotyping for both partners and IVF with preimplantation genetic testing can identify and select viable embryos, reducing miscarriage risks.

Untreated Thyroid Disorders and Diabetes Impact on RPL

Hypothyroidism, hyperthyroidism, and uncontrolled diabetes disrupt uterine environments. Hormone-regulating medications like levothyroxine or insulin therapy can correct imbalances and improve pregnancy outcomes.

Uterine Malformations and Surgical Repair Options

Congenital uterine abnormalities (e.g., septate uterus) or fibroids hinder implantation. Diagnostic imaging and hysteroscopic surgery to reshape the uterus or remove polyps can restore structural integrity for viable pregnancies.

Cervical Insufficiency: Diagnosis and Cerclage Treatment

A weakened cervix detected via ultrasound may require a cerclage (stitch) to prevent premature dilation. Regular monitoring and cerclage placement in high-risk cases significantly reduce second-trimester losses.

Lifestyle Modifications to Reduce Pregnancy Loss Risk

Smoking, heavy alcohol use, and recreational drug use increase miscarriage rates by 20-40%. Quitting these habits and adopting a fertility-focused diet with a nutritionist can enhance viability and implantation success.

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